The Harvard Program in Refugee Trauma (HPRT), originally founded at the Harvard School of Public Health, is a multi-disciplinary program that has been pioneering the health and mental health care of traumatized refugees and civilians in areas of conflict/post-conflict and natural disasters for over two decades. Its clinical program serves as a global model that has been replicated worldwide. HPRT designed and implemented the first curriculum for the mental health training of primary care practitioners in settings of human conflict, post-conflict, and natural disasters. Its training activities have been successfully conducted in Bosnia-Herzegovina, Cambodia, Croatia, Japan, and the United States. HPRT’s landmark scientific studies have demonstrated the medical and mental health impact of mass violence as well as the cultural effectiveness of its clinical treatment and training programs. Working closely with Ministries of Health throughout the world, HPRT has developed community-based mental health services primarily in existing local primary health care systems. It has also successfully established linkages to major foreign university settings. HPRT’s bicultural partnerships with international collaborators have resulted in culturally effective and sustainable programs that rely primarily on local human resources and indigenous healing systems. In order to achieve its mission, memorandums of agreements have been signed between HPRT and universities in Bosnia-Herzegovina, Italy, Japan, and Thailand. As a university-wide program, HPRT has access to the full resources and talents of Harvard University, including the Medical School (HMS), the School of Public Health, the School of Education, and the Massachusetts General Hospital (MGH). HPRT is currently administered by MGH, one of America’s oldest and most prestigious hospitals, which is a major teaching hospital of HMS.